Associate Director or Director, Clinical Scientist

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn. 

How we work:

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

How you’ll make an impact:

• Serve as the study level Clinical Scientist in immunology, with a focus on dermatologic indications, actively participating in study team meetings, vendor meetings, and data/safety monitoring committees.
• Support the design of clinical trial protocols and amendments, ensuring scientific integrity and alignment with regulatory standards. Collaborate with Translational Medicine to integrate biomarker testing and with Clinical Pharmacology to integrate pharmacokinetic sampling into trial protocols.
• Prepare and review essential documents such as medical monitoring plans, statistical analysis plans, informed consent forms, case report forms and clinical study reports.
• Support study execution as scientific subject matter expert.
• Conduct clinical data reviews, including safety monitoring activities, to ensure patient safety and data accuracy and integrity.
• Data review, cleaning, and monitoring utilizing data visualization tools, and protocol deviations review to analyze trends, identify risks and implement mitigation strategies.
• Support IRB and regulatory submissions and query responses.
• Present data and information to external investigators and internal stakeholders, contributing to meetings with governance bodies and regulatory authorities.
• Work within a matrix environment, collaborating with medical directors, regulatory affairs, translational medicine, clinical operations, data management, biostatistics, and other departments to drive clinical development programs forward. 

Skills and experience you’ll bring:

• Bachelor’s or advanced degree (MSc, PharmD, PhD) in Life Sciences or related field and 8+ years in pharmaceutical clinical drug development, with experience in global clinical trials and program execution.
• Experience in immunological diseases with an understanding of disease biology and treatment landscapes; Experience with clinical trials for dermatologic indications and endpoints is a plus.
• In-depth understanding of clinical development processes, regulatory requirements, and guidelines (FDA, EMEA, ICH, GCP).
• Strong critical-thinking, problem-solving abilities and excellent medical writing skills.
• Maintain a patient-centric mentality throughout the drug development process. 

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.  All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.

Compensation

• Kymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.
• The anticipated base salary range for this role is $160,000 – $275,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.
• Actual salary is based on a holistic evaluation of the specific role/level as well as each candidate’s depth of experience and the capabilities they bring to the position.