Director of Major Gifts- East Region

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📍 New York, NYFULL TIME💰 USD 150–175K

About this role

**This is a Hybrid role in our NYC office**

The Director of Major Gifts, Eastern Region oversees CRI’s major donor program for donors located in the geographic area assigned in order to raise the resources to fund the research necessary to advance groundbreaking discoveries and build a world immune from cancer. 


Role: 

The Major Gifts Officer oversees CRI’s major donor program for donors located in the geographic area assigned in order to raise the resources to fund the research necessary to advance groundbreaking discoveries and build a world immune from cancer. 


Responsibilities:

  • Manage a portfolio of 100 – 150 major donors ($10,000+).
  • Design and execute a strategy for all donors in the portfolio, including cultivation, stewardship, solicitation and acknowledgement.
  • Manage the annual portfolio projection process, and provide real-time updating of revenue projections.
  • Leverage CRM to track donor engagement and relationship moves management.
  • Collaborate with development, marketing and program colleagues to create compelling engagement opportunities for donors and prospective donors, including creating outreach content, events and other opportunities to connect donors to CRI’s programs, research and impact.
  • Partner with CEO, CDO and board members to grow major donor support.  Leverage events, network outreach and other approaches to connect prospective donors to CRI’s mission and impact.
  • Partner with program and finance teams to create proposals, gift agreements and reports for grants.
  • Manage reporting calendar for all gifts with reporting specifications.
  • Partner with the Director of Individual Giving and the Director of Development Operations to support the internal prospecting process for donors who have potential to give above the major donor threshold.


Requirements:

  • Minimum 5 years’ non-profit development experience with direct donor stewardship and solicitation, or similar relevant experience in mission-oriented sales
  • Minimum 2 years’ experience managing a portfolio of 75+ donors
  • A Bachelor's degree is required; a Master's degree/MBA is preferred, or equivalent work experience
  • Experience working with a diverse community of stakeholders[FK3] 
  • Excellent written and oral communication skills
  • Excellent attention to detail
  • Familiarity with the donor life-cycle and moves management
  • Knowledge of a range of giving vehicles is preferred
  • Proficient in using CRM, Google, Microsoft, Slack, professional communication tools, and project management software

Benefits:

  • 100% paid employee Health Insurance, Dental, & Vision
  • Life/AD&D Insurance
  • Short-Term Disability & Long-Term Disability 
  • 403b Company Contribution
  • Healthcare Flexible Spending Account
  • Commuter Benefits Program (Pre-Tax Transit and Parking)
  • Paid PTO

We are proud to be an equal opportunity employer, committed to fostering a diverse, inclusive, and collaborative workplace. We do not discriminate based on race, color, religion, national origin, gender, sexual orientation, age, disability, veteran status, or any other legally protected characteristic. We consider qualified applicants with criminal histories consistent with applicable laws and provide reasonable accommodations for individuals with disabilities.


We offer competitive compensation and benefits tailored to factors such as location, role complexity, and experience. For roles in New York City, the estimated base salary range is $150-175K  per year.


About Us:

The Cancer Research Institute (CRI), established in 1953 and headquartered in New York City, is the preeminent U.S. nonprofit organization dedicated to saving more lives by fueling the discovery and development of powerful immunotherapies for all cancers. 

Guided by a world-renowned Scientific Advisory Council that includes four Nobel laureates and 35 members of the National Academy of Sciences, CRI has invested over $606 million in support of research conducted by immunologists and tumor immunologists at the world's leading medical centers and universities and has contributed to many of the key scientific advances that demonstrate the potential for immunotherapy to change the face of cancer treatment. The Cancer Research Institute's research funding supports the entire continuum of basic discovery through early-stage clinical development of novel cancer immunotherapies.

Frequently Asked Questions

What is the salary for the Director of Major Gifts- East Region role at Cancer Research Institute Inc?
The listed salary for this Director of Major Gifts- East Region position at Cancer Research Institute Inc is USD 150–175K. This is an FULL TIME role.
Where is the Director of Major Gifts- East Region position at Cancer Research Institute Inc located?
This Director of Major Gifts- East Region role at Cancer Research Institute Inc is based in New York, NY. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Director of Major Gifts- East Region role at Cancer Research Institute Inc full-time or part-time?
This is listed as a FULL TIME position. It is posted as a Director of Major Gifts- East Region role in the Development department at Cancer Research Institute Inc.
Which team or department does the Director of Major Gifts- East Region at Cancer Research Institute Inc belong to?
This Director of Major Gifts- East Region position is part of the Development department at Cancer Research Institute Inc. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Director of Major Gifts- East Region position at Cancer Research Institute Inc?
Click the "Apply Now" button on this page. You will be redirected to Cancer Research Institute Inc's official application portal hosted on rippling where you can submit your application directly.
When was the Director of Major Gifts- East Region job at Cancer Research Institute Inc posted?
This Director of Major Gifts- East Region position at Cancer Research Institute Inc was posted on Jul 8, 2026. Apply as soon as possible — early applications are often reviewed first.
Director of Major Gifts- East Region
Cancer Research Institute Inc · 💰 USD 150–175K
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