Molecular Technologist I/II (High Complexity)

tempus· Tempus AI, Inc.
Apply Now ↗
📍 ChicagoFull time💰 USD 23–26
Full timeTempus AI, Inc.

About this role

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

 What you’ll do:

  • Work with a cutting-edge genomics workflow to provide high-quality next-generation sequencing data with rapid turnaround times in a clinical laboratory.

  • Perform routine quality control and laboratory maintenance procedures and proficiency testing in accordance with current laboratory SOPs:

    • Aid the Quality Control Team in routine phase-in and performance qualification of reagents and instrumentation, respectively.

    • Decontamination of laboratory equipment and work surfaces in accordance with current laboratory SOPs and routine cleaning to maintain clean, decluttered laboratory work areas.

    • Perform routine, daily laboratory maintenance of NGS instrumentation.

    • Participate in routine proficiency testing as required to ensure accuracy and reliability of laboratory testing results.

  • Read and understand NGS SOPs required to perform routine clinical workflow procedures. Participate in the review, editing, and/or creation of NGS procedures and documentation. 

  • Demonstrate mastery of NGS workflows, which are performed under direction of more senior and/or lead technologists and NGS supervisors, monitor and coordinate the training of other technologists, along with assisting in optimization of training documents. 

  • Perform routine diagnostic oncology testing using complex molecular-based procedures with a high degree of quality and in accordance with established SOPs.

    • Perform next-generation sequencing, including DNA/RNA quantification and qualification; NGS library preparation and library clean-up;  hybridization and capture cleanup and quantification; and sequencing on the Illumina Novaseq6000 and NovaX platforms. 

    • Enter clinical patient data obtained from routine testing into the Laboratory Information Management System (LIMS).

  • Maintain competency to perform all assigned molecular biology protocols and satisfy continuing education requirements of 12 CEUs  in the field of oncology or molecular biology on a yearly basis in accordance with CAP, CLIA, NYSDOH regulations.

Qualifications:

Must have:

  • The following educational requirements:

    Degree:
    • BS in medical technology, clinical laboratory science, chemical, physical or biological science. 

    • MS in medical technology, clinical laboratory science, chemical, physical or biological science OR

    • Curriculum: At least 60 semester hours, or equivalent, from an accredited institution that, at a minimum, includes either:

      • 24 semester hours of medical laboratory technology courses; or 

      • 24 semester hours of science courses that include: 

        • 6 semester hours of chemistry; 

        • 6 semester hours of biology; and

        • 12 semester hours of chemistry, biology, or medical laboratory technology in any combination.

  • Experience: 1 to 2+ years of post-baccalaureate (post-BS degree) clinical experience in a CAP/CLIA high-complexity laboratory (such as CORE, molecular pathology, molecular diagnostics, microbiology, or forensics/drug testing labs, etc), with at least 6 months to 1 year experience in NGS workflows and molecular biology testing techniques, such as nucleic acid extraction, library preparation, hybridization/capture and sequencing. 

    • Human sample testing experience in a CAP/CLIA high complexity clinical laboratory setting is required.

  • Excellent communication skills.

  • Thrives in a fast-paced environment.

  • Ability to work with others to plan and carry out scientific programs.

  • Self-driven and works well in an interdisciplinary team with minimal direction.

  • Strong desire to build products that will save lives and change the course of cancer.

  • Impeccable attention to detail.

Highly Desirable:

  • Experience with robotics and automated liquid handling systems.

  • Knowledge of LIMS platforms and various computer systems.

  • Experience with Illumina (NovaSeq 6000)  and next-generation sequencing.

  • Work in an oncology or comprehensive genomics testing lab.

  • Work in a CLIA/CAP high-complexity laboratory.

Please note that shift assignment is based on technical level, experience, and current business needs. Hiring Team will go through current open shifts during Interview Process.

Shift Options:

  • Sun-Wed or Wed-Sat (+ skip shifts); PM
  • Sun-Wed or Wed-Sat (+ skip shifts); AM
  • 3rd Shift/ON: Sun-Thurs, 11p-730a or Tues-Sat, 11p-730a

CHI Hourly Rate: $23.25-$25.50


The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. 

Frequently Asked Questions

What is the salary for the Molecular Technologist I/II (High Complexity) role at tempus?
The listed salary for this Molecular Technologist I/II (High Complexity) position at tempus is USD 23–26. This is an Full time role.
Where is the Molecular Technologist I/II (High Complexity) position at tempus located?
This Molecular Technologist I/II (High Complexity) role at tempus is based in Chicago. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Molecular Technologist I/II (High Complexity) role at tempus full-time or part-time?
This is listed as a Full time position. It is posted as a Molecular Technologist I/II (High Complexity) role in the Tempus AI, Inc. department at tempus.
Which team or department does the Molecular Technologist I/II (High Complexity) at tempus belong to?
This Molecular Technologist I/II (High Complexity) position is part of the Tempus AI, Inc. department at tempus. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Molecular Technologist I/II (High Complexity) position at tempus?
Click the "Apply Now" button on this page. You will be redirected to tempus's official application portal hosted on workday where you can submit your application directly.
When was the Molecular Technologist I/II (High Complexity) job at tempus posted?
This Molecular Technologist I/II (High Complexity) position at tempus was posted on Aug 5, 2026. Apply as soon as possible — early applications are often reviewed first.
Molecular Technologist I/II (High Complexity)
tempus · 💰 USD 23–26
Apply for this role ↗

You'll be redirected to tempus's official application page on Workday.