SOX Compliance Program Manager - Salesforce

twistbioscience· General & Administration
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📍 USA - South San Francisco, CA💰 USD 110K–133K

About this role

Salesforce SOX Compliance & Release Manager (Hybrid in South San Francisco)

Summary

The Salesforce SOX Compliance & Release Manager will maintain and execute our Sarbanes-Oxley (SOX) and Information Technology General Controls (ITGC) frameworks across our enterprise Salesforce environment.

This role will handle day-to-day audit support, access controls, and release coordination, and serve as an operational point of contact for Internal Audit, external auditors (EY), and cross-functional teams to ensure that change management policies and user lifecycle processes are consistently executed and documented.

Core Responsibilities

SOX & ITGC Operational Compliance

  • Audit Support & Evidence Gathering: Assist in pulling walkthrough samples, change tickets, approval logs, and system evidence for external auditors (EY) and Internal Audit.
  • Identity & Access Management (IAM): Process user access, role assignments, and timely deactivations in accordance with SLA metrics via Jira and ServiceNow.
  • Access & Role Reviews: Perform scheduled quarterly and annual user access and profile audits to prevent Segregation of Duties (SoD) conflicts.
  • Checklists & Documentation: Maintain operational compliance checklists, record change logs, and document system configurations for all Salesforce components and custom solutions.
  • Focus on testing, monitoring, and evidencing control effectiveness for regulatory/SOX programs; strong fit for ITGC walkthroughs, sampling, documentation, and audit support.

Release Coordination & Execution

  • Release Logistics: Coordinate release schedules and deployment activities across Salesforce environments and connected integrations.
  • Communication & Verification: Draft release notifications for cross-functional stakeholders and assist with post-production verification testing following system deployments.
  • Ticket & Pipeline Tracking: Ensure all deployment requests in Jira/ServiceNow have appropriate change approvals, business sign-offs, and pre/post-deployment documentation attached before release.

Key Qualifications

  • Experience: 3 to 5 years of experience in program management, compliance support, audit execution and  Salesforce administration within a regulated environment.
  • Salesforce Knowledge: Hands-on experience with Salesforce user administration, profiles, permission sets, roles, and basic change management (Sandboxes, deployment steps).
  • Process & Tooling Skills: Active experience using Jira or ServiceNow for ticket management, access controls, and release tracking.
  • Audit Readiness: Familiarity with OTC and  ITGC principles, SOX compliance concepts, and auditor evidence-gathering workflows.
  • Education & Certifications:
    • Bachelor’s degree in Information Systems, Business Administration, or related field.
    • Preferred: Salesforce Certified Administrator
    • Compliance & Regulatory > Compliance 

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.
San Francisco Bay Area Pay Range
$110,000$132,500 USD

Frequently Asked Questions

What is the salary for the SOX Compliance Program Manager - Salesforce role at twistbioscience?
The listed salary for this SOX Compliance Program Manager - Salesforce position at twistbioscience is USD 110K–133K. This is an full-time role.
Where is the SOX Compliance Program Manager - Salesforce position at twistbioscience located?
This SOX Compliance Program Manager - Salesforce role at twistbioscience is based in USA - South San Francisco, CA. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Which team or department does the SOX Compliance Program Manager - Salesforce at twistbioscience belong to?
This SOX Compliance Program Manager - Salesforce position is part of the General & Administration department at twistbioscience. See the full job description for more information about the team structure and responsibilities.
How do I apply for the SOX Compliance Program Manager - Salesforce position at twistbioscience?
Click the "Apply Now" button on this page. You will be redirected to twistbioscience's official application portal hosted on greenhouse where you can submit your application directly.
When was the SOX Compliance Program Manager - Salesforce job at twistbioscience posted?
This SOX Compliance Program Manager - Salesforce position at twistbioscience was posted on Aug 26, 2026. Apply as soon as possible — early applications are often reviewed first.
SOX Compliance Program Manager - Salesforce
twistbioscience · 💰 USD 110K–133K
Apply for this role ↗

You'll be redirected to twistbioscience's official application page on Greenhouse.